Frontier 丨 lung cancer diagnosis, quit smoking, survival rate can be increased by 29%

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Frontier 丨 lung cancer diagnosis, quit smoking, survival rate can be increased by 29%

2022-01-18 12:09:22 48 ℃

According to a study published in "Chest Oncology Magazine (JTO), the total survival (OS) rate of lung cancer patients with smoking cess cancer was increased by 29% compared to patients who were confirmed after diagnosis.

Dr. Saverio Caini, Italy Florence Cancer Research, Prevention and Clinical Network, Suminated the current scientific evidence of whether to quit smoking on patients after the diagnosis of lung cancer 21 articles published before October, covering more than 10,000 patients. "Coatter" is defined as a person who quits smoking during treatment or during the treatment of lung cancer (up to 12 months) during the diagnosis of lung cancer.

The article published by JTO shows that no matter how tissue subtypes, there is a better OS (difference P value = 0.812). Integrated all research, smoking cessation with OS improved SRR is 0.71, this benefit in non-small cell lung cancer (SRR = 0.77), small cell lung cancer (SRR = 0.75), hybrid or unclear histological type (SRR = 0.81) is consistent.

It is worth noting that when analyzing the study of patients with lung cancer in patients with diagnosis or after diagnosis, "the correlation between quitting smoking and OS improvement is often stronger.

Table 1. Diagnostic or diagnosis before and after the diagnosis

Smoking cessation may play a positive effect on the survival rate of patients with lung cancer, because the tobacco fog will promote the growth, progress and communication of tumors; reduce the efficacy and tolerance of radiation therapy and systemic treatment; according to this study, smoking has increased postoperative The risk of complications and second original processes.

"Our research shows that even after lung cancer is diagnosed, clinicians should also inform patients with lung cancer to quit smoking, and provide them with the necessary quit smoking support. Smoking cessation plan must be fully integrated into multi-disciplinary cancer treatment programs," Dr. Caini said.

There are also some limitations of this study, such as research design, including patient characteristics, tobacco exposure and duration of tobacco exposure and duration. All research included in high-income countries.